Source: RGD

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
UPP1 Q16831 uridine phosphorylase 1 Enzyme 3.8E-04 0.682 0.462 1
TNFRSF1A P19438 TNF receptor superfamily member 1A 0.99 0.409 0.923 23
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962 90
TH P07101 tyrosine hydroxylase 1.7E-06 0.462 0.885 18
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962 40
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962 17
SNAP91 O60641 synaptosome associated protein 91 Transporter 1.00 0.638 0.538 1
SMO Q99835 smoothened, frizzled class receptor G-protein coupled receptor 4.3E-07 0.489 0.731 5
SLPI P03973 secretory leukocyte peptidase inhibitor Enzyme modulator 9.0E-04 0.449 0.846 8
SLC9A1 P19634 solute carrier family 9 member A1 Transporter 0.79 0.550 0.731 15
SLC2A1 P11166 solute carrier family 2 member 1 Transporter 0.99 0.388 0.808 8
SLC12A2 P55011 solute carrier family 12 member 2 Transporter 0.96 0.552 0.808 7
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885 20
SERPINF1 P36955 serpin family F member 1 Enzyme modulator 7.8E-08 0.460 0.846 18
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885 48
RUNX1 Q01196 RUNX family transcription factor 1 Transcription factor 0.65 0.425 0.808 3
RPL28 P46779 ribosomal protein L28 Nucleic acid binding 0.77 0.839 0.192 1
RGMA Q96B86 repulsive guidance molecule BMP co-receptor a 0.16 0.656 0.692 3
PTPRZ1 P23471 protein tyrosine phosphatase receptor type Z1 Enzyme 0.99 0.623 0.615 6
PLAT P00750 plasminogen activator, tissue type Enzyme 5.7E-05 0.445 0.885 15
PDGFRB P09619 platelet derived growth factor receptor beta Kinase 0.90 0.416 0.846 16
PDGFRA P16234 platelet derived growth factor receptor alpha Kinase 1.00 0.415 0.808 12
PAWR Q96IZ0 pro-apoptotic WT1 regulator 9.0E-02 0.542 0.846 7
PARP1 P09874 poly(ADP-ribose) polymerase 1 3.3E-04 0.389 0.923 12